【题目】They are now in great need of help so your support will certainly make a(n)______.
A.attempt
B.difference
C.effort
D.remark

【答案】B
【解析】考查固定短语。句意：他们现在正非常需要帮助，你的支持肯定会起很大作用。make a difference “有影响，起作用”；make an attempt“企图，尝试”； make an effort“努力”； make a remark“评论”，选B。